[1] Wang Jue, Li Wenyuan, Wang Zhigong, et al. Function electrical stimulation circuitfor neural signal regeneration system [J]. Journal of Southeast University (English Edition), 2007, 23 (4): 512-515. [doi:10.3969/j.issn.1003-7985.2007.04.007]

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Function electrical stimulation circuitfor neural signal regeneration system()

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Journal of Southeast University (English Edition)[ISSN:1003-7985/CN:32-1325/N]

Volumn:

23

Issue:

2007 4

Page:

512-515

Research Field:

Circuit and System

Publishing date:

2007-12-30

Info

Title:

Function electrical stimulation circuitfor neural signal regeneration system

Author(s):

Wang Jue¹;  2;  Li Wenyuan¹;  Wang Zhigong¹

¹Institute of RF- & OE-ICs, Southeast University, Nanjing 210096, China
²College of Integrated Circuits, Southeast University, Nanjing 210096, China

Keywords:

low-power;  rail-to-rail;  neural signal;  voltage drive

PACS:

TN432

DOI:

10.3969/j.issn.1003-7985.2007.04.007

Abstract:

A low-power, high-gain circuit for function electrical stimulation(FES)is designed for the microelectronic neural signal regeneration system based on CSMC(CSMC Technologies Corporation)0.6 μm CMOS(complementary metal-oxide-semiconductor transistor)technology.It can be used to stimulate microelectrodes connected with the nerve bundles to regenerate neural signals.This circuit consists of two stages:a full differential folded-cascode amplifier input stage and a complementary class-AB output stage with an overload protection circuit.The rail-to-rail input and output stages are used to ensure a wide range of input and output voltages.The simulation results show that the gain of the circuit is 81 dB;the 3 dB-bandwidth is 295 kHz.The chip occupies a die area of 1.06 mm×0.52 mm.The on-wafer measurement results show that under a single supply voltage of+5 V, the DC power consumption is about 7.5 mW and the output voltage amplitude is 4.8 V.The chip can also run well under single supply voltage of +3.3 V.

References:

[1] Wang Zhigong, Lü Xiaoying, Gu Xiaosong, et al.Microelectronic detecting, processing and rebuilding central neural signals [C]//The Third Joint Symposium on Opto and Microelectronic Devices and Circuits.Wuhan, China, 2004:22-26.
[2] Li Wenyuan, Wang Zhigong, Zhang Zhenyu.Low-power CMOS IC for function electrical stimulation of nerves[J].Chinese Journal of Semiconductors, 2007, 28(3):393-397.
[3] Zhang Zhenyu.Design of implanted central nerve recovery system and its stimulation circuits [D].Nanjing:Institute of RF- & OE-ICs of Southeast University, 2006.(in Chinese)
[4] Xie Xiang, Zhang Chun, Wang Zhihua.Application and development of microelectronic technology in biology and medicine [J].Journal of Circuits and Systems, 2003, 8(2):80-85.(in Chinese)
[5] Zhang Weizhen.Biomedical electronics [M].Beijing:Tsinghua University Press, 1990:6-24.(in Chinese)
[6] Razavi Behzad.Design of analog CMOS integrated circuits [M].Singapore:McGraw-Hill Book Co-Singapore, 2001:325-326.
[7] Hogervorset R, Tero J P, Eschauzier R G H, et al.A compact power-efficient 3 V CMOS rail-to-rail input/output operational amplifier for VLSI cell libraries [J].IEEE Journal of Solid-State Circuits, 1994, 29(12):1505-1513.
[8] Allen Phillip E, Holberg Douglas R.CMOS analog circuit design [M]. Translated by Feng Jun, Li Zhiqun.Beijing:Publishing House of Electronics Industry, 2002:103-116.(in Chinese)
[9] Gray Paul R, Hurst Paul J, Lewis Stephen H, et al.Analysis and design of analog integrated circuits [M].4th ed.New York:John Wiley & Sons, Inc, 2001:384-391;425-446;846-847.
[10] Sekerkiran, B.A compact rail-to-rail output stage for CMOS operational amplifiers [J].IEEE Journal of Solid-State Circuits, 1999, 34(1):107-110.

Memo

Memo:

Biographies: Wang Jue(1983—), female, graduate;Li Wenyuan(corresponding author), male, doctor, associate professor, lwy555@seu.edu.cn.

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