|Table of Contents|

[1] Dai Lin, Zhang Yong, Hu Chi, Qian Hongliang, et al. Mathematical modeling for ultrasonic-assisted extractionof arctigenin from acid hydrolyzed FructusArctii [J]. Journal of Southeast University (English Edition), 2017, 33 (3): 362-369. [doi:10.3969/j.issn.1003-7985.2017.03.017]

Mathematical modeling for ultrasonic-assisted extractionof arctigenin from acid hydrolyzed FructusArctii()

Journal of Southeast University (English Edition)[ISSN:1003-7985/CN:32-1325/N]

2017 3
Research Field:
Biological Science and Medical Engineering
Publishing date:


Mathematical modeling for ultrasonic-assisted extractionof arctigenin from acid hydrolyzed FructusArctii
Dai Lin Zhang Yong Hu Chi Qian Hongliang Wang Zhixiang
School of Engineering, China Pharmaceutical University, Nanjing 210009, China
FructusArctii acid hydrolysis ultrasonic-assisted extraction arctigenin mathematical model
A mathematical model based on Fick’s first law was established to describe the process of ultrasonic-assisted extraction of arctigenin from acid hydrolyzed FructusArctii. Acid hydrolization with hydrochloric acid promotes the conversion of arctiin to arctigenin in the arctiin-rich active pharmaceutical ingredient, and the hydrolyzed products were further examined to investigate the process setup. By considering the mechanism of the extraction process and experimental data, the effects of parameters including solvent to solid ratio, particle size of hydrolyzed samples, ethanol volume fraction, ultrasound power, extraction temperature and extraction time on concentration of arctigenin were analyzed in detail. The model was suitable for simulating the process of ultrasonic-assisted extraction of arctigenin. The simulation results of the model agree well with experimental data with the deviation below 13%, indicating that the mathematical model can provide valuable guidance for the extraction of arctigenin from acid hydrolyzed FructusArctii.


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Biographies: Dai Lin(1981—), male, master, lecturer; Wang Zhixiang(corresponding author), male, doctor, professor, 1443590147@qq.com.
Foundation items: The National Natural Science Foundation of China(No.21406272, 21676291), the Fundamental Research Funds for the Central Universities(No.2632017ZD01), Jiangsu Planned Projects for Postdoctoral Research Funds(No.1402060B).
Citation: Dai Lin, Zhang Yong, Hu Chi, et al. Mathematical modeling for ultrasonic-assisted extraction of arctigenin from acid hydrolyzed FructusArctii[J].Journal of Southeast University(English Edition), 2017, 33(3):362-369.DOI:10.3969/j.issn.1003-7985.2017.03.017.
Last Update: 2017-09-20