[1] Zhao Huan, Xiao Guomin, Lü Jianhua,. Separation of picolines by dissociation extraction [J]. Journal of Southeast University (English Edition), 2005, 21 (1): 68-72. [doi:10.3969/j.issn.1003-7985.2005.01.015]
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Separation of picolines by dissociation extraction(
)
)Journal of Southeast University (English Edition)[ISSN:1003-7985/CN:32-1325/N]
- Volumn:
- 21
- Issue:
- 2005 1
- Page:
- 68-72
- Research Field:
- Chemistry and Chemical Engineering
- Publishing date:
- 2005-03-30
Info
- Title:
- Separation of picolines by dissociation extraction
- Author(s):
- Zhao Huan; Xiao Guomin; Lü Jianhua
- Department of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, China
- Keywords:
- 3-picoline; 4-picoline; separation; dissociation extraction; orthogonal test
- PACS:
- TQ028.8
- DOI:
- 10.3969/j.issn.1003-7985.2005.01.015
- Abstract:
- The separation of the by-product(The volume fraction of 3-picoline is 68.472 2% and 4-picoline 26.517 6%.)in the synthesis of pyridine by dissociation extraction was studied.Six separation conditions of the dissociation extraction—the kind and the dosage of extractant and organic solvent, the concentration of the extractant and separation temperature—were investigated.Different levels of each factor were chosen to form an orthogonal test of six factors and five levels.The results show that the volume ratio of 3-picoline and 4-picoline in organic phase is the highest when 24 mL picolines are separated at 0 ℃ by 2.0 mol/L p-toluenesulfonic and n-heptane whose dosages are 40 mL and 48 mL, respectively.The effect of the separation is considerably improved with repetition test.This process of dissociation extraction has commendable potential for industrial exploitation.
References:
[1] Zhao Huan, Xiao Guomin.Separation of mixtures of 3-methylpyridine with 4-methylpyridine [J].Science and Technology in Chemical Industry, 2003, 12(4):52-56.(in Chinese)
[2] Sun Xuefei, Han Fujun, Qin Wei, et al.Dissociation extraction and its applications[J].Modern Chemical Industry, 2000, 20(5):14-17.(in Chinese)
[3] Anwar M M, Hanson C, Patel A N, et al.Dissociation extraction, Part Ⅱ:Multi-stage extraction [J].Trans Instn Chem Engrs, 1973, 51:151-158.
[4] Anwar M M, Arif A S, Pritchard D W.Multistage separation of quinoline and iso-quinoline by dissociation extraction [J].Solvent Extractive and Ion Exchange, 1998, 16(47):931-935.
[5] Wu Guisheng.Experiment design and data processing[M].Beijing:Metallurgy Industry Press, 1997.(in Chinese)
[6] Anwar M M, Hanson C, Patel A N.Detection of pyridine derivatives [J].J Chromat, 1968, 34(5):529.
[7] Gaikar Vilas G, Mahapatra Alpana, Sharma Man Mohan.Separation of close boiling point mixtures(p-Cresol/m-Cresol, Guaiacol/Alkylphenols, 3-picoline/4-picoline, substituted anilines)through dissociation extractive crystallization[J].Ind Eng Chem Res, 1989, 28(2):199-204.
[8] Sun Chunxia, Peng Panying, Wang Yuping, et al.Separation of 3-picoline and 4-picoline [J].Journal of Nanjing Normal University (Engineering and Technology), 2004, 4(2):11-13.(in Chinese)
Memo
- Memo:
- Biographies: Zhao Huan(1981—), female, graduate;Xiao Guomin(corresponding author), male, doctor, professor, xiaogm@seu.edu.cn.