[1] Zhu Dongjuan, Wang Xunheng, Ruan Zongcai,. Numerical study of resting-state fMRI based on kernel ICA [J]. Journal of Southeast University (English Edition), 2010, 26 (1): 78-81. [doi:10.3969/j.issn.1003-7985.2010.01016]

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Numerical study of resting-state fMRI based on kernel ICA()

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Journal of Southeast University (English Edition)[ISSN:1003-7985/CN:32-1325/N]

Volumn:

26

Issue:

2010 1

Page:

78-81

Research Field:

Biological Science and Medical Engineering

Publishing date:

2010-03-30

Info

Title:

Numerical study of resting-state fMRI based on kernel ICA

Author(s):

Zhu Dongjuan;  Wang Xunheng;  Ruan Zongcai

Research Center for Learning Science, Southeast University, Nanjing 210096, China

Keywords:

kernel independent component analysis;  principal component analysis;  functional magnetic resonance imaging(fMRI);  resting-state

PACS:

R318.04

DOI:

10.3969/j.issn.1003-7985.2010.01016

Abstract:

In order to facilitate the extraction of the default mode network(DMN), reduce the data complexity of the functional magnetic resonance imaging(fMRI)and overcome the restriction of the linearity of the mixing process encountered with the independent component analysis(ICA), a framework of dimensionality reduction and nonlinear transformation is proposed. First, the principal component analysis(PCA)is applied to reduce the time dimension 153 594×128 of the fMRI data to 153 594×5 for simplifying complexity computation and obtaining 95% of the information. Secondly, a new kernel-based nonlinear ICA method referred as the kernel ICA(KICA)based on the Gaussian kernel is introduced to analyze the resting-state fMRI data and extract the DMN. Experimental results show that the KICA provides a better performance for the resting-state fMRI data analysis compared with the classical ICA. Furthermore, the DMN is accurately extracted and the noise is reduced.

References:

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Memo

Memo:

Biographies: Zhu Dongjuan(1986—), female, graduate; Ruan Zongcai(corresponding author), male, doctor, lecturer, rzc.rcls@seu.edu.cn.
Foundation item: Key Academic Discipline during the 11th Five-Year Plan Period of Jiangsu Province.
Citation: Zhu Dongjuan, Wang Xunheng, Ruan Zongcai.Numerical study of resting-state fMRI based on kernel ICA[J]. Journal of Southeast University(English Edition), 2010, 26(1): 78-81.

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